from Hacker News

An ALS hot spot in the French Alps associated with genotoxic fungi

by melenaboija on 3/11/25, 12:20 AM with 1 comments

  • by robocat on 3/11/25, 4:24 AM

    Summary:

      P.S. asked whether wild fungi (specifically, False Morels) that generate a genotoxin (monomethylhydrazine) related by mechanism to cycad methylazoxymethanol, a leading candidate for the etiology of Guam ALS, might have been used as a food item in Montchavin. This question generated a more intensive examination of the sources and uses of food items (notably wild mushroom species) by the Montchavin-related ALS cases and controls, whereupon the link between ALS and False Morels was discovered.