from Hacker News

Psychotic disorders with cognitive impairment have brain metabolic dysregulation

by arijo on 2/24/25, 7:38 PM with 3 comments

"Conclusions: Our results demonstrate that psychotic disorders with greater cognitive impairment have greater brain metabolic dysregulation, with more reductive stress and decrease in energy metabolic rate markers. This provides new evidence for the potential of emerging metabolic therapies to treat cognitive deficits in psychotic disorders."

What this means is that metabolic interventions like ketogenic diet that improve brain metabolic function may be helpful in cognition for patients with psychotic illness. Or, in lay terms, "with better fuel for the brain, people with the most serious mental illnesses may be able to think better."

https://academic.oup.com/schizophreniabulletin/advance-article-abstract/doi/10.1093/schbul/sbaf003/7984396?redirectedFrom=fulltext&login=false

  • by PaulHoule on 2/24/25, 7:58 PM

    It's a classic rookie mistake on HN to submit a link as part of a discussion. Trouble is, people can't click on the link.

    If you want people to have a discussion about a link submit the link, if you want to kick off the discussion with some commentary than feel free to post a comment.

    Please delete this post and re-submit!

    (Personally as a schizotype I think this is a super-interesting topic and it's also one that has been circulating for some time!)