from Hacker News

New Targeted Cancer Vaccines Eliminate Tumors and Prevent Recurrence in Mice

by rchaudhary on 8/23/22, 2:28 PM with 5 comments

• by adamredwoods on 8/23/22, 4:37 PM

  The article is about the lipid nano-particle delivery system, leaving the vaccine as a set of possible substances. The paper is paywalled.

  More on lipid nano-particle delivery: https://www.nature.com/articles/s41578-021-00358-0

  Looks like the authors started a company: https://www.hopewell-tx.com/

  Delivery systems are just as important as part of the cure, or the actual substance killing the tumor cells. If we had better targeted delivery for platinum-based chemo, we could try a bit more things for different patients (increased dosage, low-dose infusions for long-term plans).

  Albumin-bound paclitaxol is an example of this.

• by helloworld11 on 8/23/22, 3:14 PM

  Not to denigrate the scientific effort and achievement of the people creating this, but if even a fraction of what our medicine can do in mice were at all workably, usefully applicable to humans, we'd be living dream lives of medical therapy by now. Too bad so much that works in said mice would instead simply kill us stone dead, or just do nothing.