from Hacker News

Effectiveness of a Third Dose of Vaccines in Preventing Covid-19 Hospitalization

by drocer88 on 1/28/22, 3:15 PM with 2 comments

  • by kashunstva on 1/28/22, 7:34 PM

    > Second, VE [vaccine effectiveness] associated with newly emergent variants, including Omicron, was not assessed.

    Insofar as the Omicron variant is the dominant strain, it leaves open the question of VE *today*. There's reason to expect improvement in VE of a 3-dose strategy over a 2-dose strategy, but perhaps the magnitude of the Δ would be less. Hard to say.

    It's the difficult thing about studying vaccine efficacy with this virus: by the time the study has recruited enough participants, enough time has elapsed to measure an effect and the data are analyzed and published, a new variant emerges that casts uncertainty on the applicability of the data.