from Hacker News

Opaque drug pricing in the U.S.

by elberto34 on 3/12/17, 7:05 PM with 117 comments

  • by e15ctr0n on 3/12/17, 8:32 PM

    > backroom deals by assorted players in the healthcare food chain

    The articles dances around the details of who these players are and how they conspire to push up drug prices in America. This article captures the dynamics very well: http://www.diabetesforecast.org/2016/mar-apr/rising-costs-in...

    and the accompanying graphic is the picture that is worth a thousand words: http://www.diabetesforecast.org/2016/mar-apr/images/insulin-...

    A good summary from a more recent article on insulin prices: https://medium.com/insulin-report/why-does-insulin-cost-so-m...

    Drug manufacturers make insulin available to insurance companies at a much lower price via middlemen called pharmacy benefit managers. The difference between the list price and the lower price negotiated by the pharmacy benefit managers is called the spread. Part of the spread is pocketed by the pharmacy benefit managers, leading to a perverse incentive in which the higher the list price of the drug, the higher the earnings of the pharmacy benefit managers. The price rise affects the uninsured and under-insured the most, many of whom can no longer afford to buy insulin at its list price any more.

  • by cloakandswagger on 3/12/17, 8:33 PM

    Pharmaceuticals are only about 10% of all healthcare costs [1].

    The vast majority of healthcare spending goes to hospitals and doctors, yet the political environment hyper focuses on drugmakers. Why isn't there a larger focus on reducing the costs of hospitals and healthcare professionals?

    [1] http://www.pfizer.com/files/about/Position-Role-of-Pharmaceu...

  • by awinter-py on 3/12/17, 11:03 PM

    Lack of price transparency is the fatal flaw in nationalized healthcare. I'm endlessly surprised it's not top on the list at every debate.

    Lasik is an out-of-pocket procedure. It has the highest satisfaction rate of any surgery and the price has gone steadily down since it was introduced.

    Should all healthcare be out of pocket? Maybe not. But if most consumers purchased most health services retail instead of via invisible negotiated prices, insurance would get cheaper too. (And until that happens, prices will continue to go up).

    Medicare set a cap on the first 30 days post heart-attack care in the 90s and hospitals respected it -- but day 31 got a lot more expensive.

  • by mikeyouse on 3/12/17, 7:59 PM

    I think this ACS article describes the situation very well:

    http://cen.acs.org/articles/95/i9/Pushback.html

    It's long but a very thorough treatment of the problem. The existing pharma system is very, very profitable and there is a ton of resistance to anything to rock that boat. Lately profitability has been coming from price increases instead of innovation but pharma is okay with that as long as it lets them pay billions in dividends.

  • by wmccullough on 3/12/17, 8:57 PM

    I feel a lot of people in this thread must not have any chronic health conditions. I see comments about how this is a free market and that this is okay. I suspect if Pharma was bankrupting you like it is me, your stance might change.
  • by justinph on 3/12/17, 8:33 PM

    I think the LA Times takes the crown for the most unperformant tracker and advertising infested legitimate news site. Ghostery counts 88 advertisers / tracking scripts on this page and it still not done loading. What a disaster.
  • by tcj_phx on 3/12/17, 9:29 PM

    This article talks about absurd pricing for new patented delivery mechanisms for old generic drugs - the epipen, the evizio naloxone auto-injector (and presumably the Narcan insufflation device).

    Anyone who might need to deliver these drugs -- to their allergic kid, addict friend, etc -- ought to learn how to use a syringe, and skip the price gouging. Someone on the opiates subreddit sent me a couple vials of naloxone and some needles - I sent a donation to cover shipping & handling.

    Naloxone is $0.50/mg, when you buy a gram at a time: http://www.sigmaaldrich.com/catalog/substance/naloxonehydroc... - I tried to buy some naloxone powder from a different company, but they wouldn't sell it to me. I wonder if Sigma Aldrich would...

    I think more attention should be drawn to prescription drugs that harm patients. For example, the caller to a NPR Science Friday segment [1] was annoyed that her doctor made her "manic and suicidal" with the depo-provera injection, and that this awful drug is still on the market.

    [1] http://www.sciencefriday.com/segments/looking-beyond-condoms... (The first caller was at 8min30sec)

  • by rayiner on 3/12/17, 8:56 PM

    The title is misleading. It says "value" but only ever discusses "price" which is a related by distinct concept. That confusion is actually emblematic of the wrong-headed approach the media takes to the pharmaceutical industry: it ignores the value created by innovations in drugs.

    Just in my adult life there has been enormous advances in treating HIV, Hep-C, and various cancers. When I was a kid in the 1990s, HIV was a death sentence people talked about in hushed tones. With modern anti-retrovirals:

    > What did this do to life expectancy? In 1996-97 the life expectancy at age 20 of an HIV-positive person was 19 years, in other words they could only expect to live, on average, in the absence of any improvement in treatment, till they were 39. By 2011, this had improved to 53 years, i.e. death on average at 73.

    (http://www.aidsmap.com/Life-expectancy-in-HIV-positive-peopl...)

    What is the value of living to 73 versus living to 39? Big enough where the $10-12k annual cost of anti-retrovirals is a bargain in comparison. Probably a way better bargain than a $700 iPhone.

    When you make something that creates a ton of value for people, you are able to charge a lot for it and make a big profit. There is nothing nefarious about that, and indeed those outsized profits are essential to making the system work. Turning drugs into a price-regulated ghetto is going to do nothing more than drive investors to areas like advertising where nobody will blink when they see a 30% profit margin. Unless you're willing to replace that private investment with public investment (as we have done in the defense industry), that's a terrible idea.

  • by gist on 3/12/17, 10:22 PM

    > There’s a good reason why U.S. drug prices are so much higher than what people pay in other countries. Most other developed nations place limits on how much drug companies can charge to prevent them from taking advantage of the sick. A fair profit is fine. Price gouging is not.

    Ok so what is happening here if it's not clear is this. People in the US are subsidizing so that people in those countries don't pay as much. Point being if people in the US paid the same price (in theory) the drug companies wouldn't make enough money to support their operations. As a result prices would rise for everyone and drugs in the US would cost less. I guess it's to simple for our government to enact some kind of 'most favored nation' clause whereby the discounts given to other countries must be given here. My guess is that that doesn't happen simply because it works in the favor of the drug companies (who will lobby) to have the current system.

  • by maxxxxx on 3/13/17, 12:49 AM

    The Republicans could have shown their seriousness about free market healthcare and consumer oriented lately if they had required medical pricing (and quality numbers) to be transparent so patients can make an informed decision.

    Of course they didn't but I think this needs to be pointed out repeatedly.

  • by CamperBob2 on 3/12/17, 8:38 PM

    Complementary headline on Pharma News: "Software really, really doesn't want you to know the true value of its code"
  • by imaginenore on 3/12/17, 8:23 PM

    1) An article discussing the prices of drugs that doesn't talk about the costs of RnD and the FDA approval process is pointless.

    2) We're in a free market, companies can charge a billion dollars a pill if they want to.

  • by randyrand on 3/12/17, 8:28 PM

    edit: The post title changed, it used to reference drug value

    the value of a drug is the amount someone is willing to pay for it. different for everyone.

    while im a big proponent of lower drug costs and agree drugs cost more than they should/could,

    drugs are typically very underpriced compared to their actual value. a drugs actual value to the a person can be tremendous. if we charged people the same amount as the value it brings them, they would not buy it! it would be a wash! since lots a people are buying lots of drugs, we know drugs are typically priced under their real value; that's a good thing!!

    in other words, talking about the value of a drug if you're arguing to lower their cost is the last thing you want to do!